Asian Journal of Case Reports in Medicine and Health

Post-Artesunate Late Haemolytic Anemia in a 17-Month-Old Infant Followed for Severe Malaria at the Yalosase Health Center, Isangi, DR Congo

Dieudonné Lobela Bumba *

Infectious and Tropical Diseases Department, National University Hospital of Fann, Dakar, Senegal and Higher Institute of Medical Techniques of Yangambi, DR Congo.

Issa Yakusu Issa

Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.

Ossinga Bassandja

Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.

Mankulu N’Sila

University of Cepromad, Faculty of Public Health and Medicine of Proximity, Kisangani, DR Congo.

Beatrice Lisimo

Cinquantenaire Hospital of Kisangani, Kisangani, DR Congo.

Bruce Wembolua Shinga

Infectious and Tropical Diseases Department, National University Hospital of Fann, Dakar, Senegal.

Kendewa sabiti

Higher Institute of Medical Techniques of Yangambi, DR Congo.

Bokanga Ekelenge

Department of Gynecology-Obstetric, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.

Francy Baelongandi Folo

Provincial Health Division, Tshopo, DR Congo.

Atoba Bokele

Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.

*Author to whom correspondence should be addressed.

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Abstract

Artesunate is an artemisinin derivative with rapid and potent parasiticidal power. However, cases of delayed hemolytic anemia described in the literature can be fatal, especially in children. We report a rare case of late hemolytic anemia in an infant. This was a 17 month old infant with a history of severe malaria treated with artesunate two weeks ago, seen in consultation for hemolytic anemia with negative GE. Both HBsAg and anti-HCV serology were negative. Considering the context, the diagnosis of post-artesunate late hemolytic anemia was retained and the patient had progressed well after transfusion.

Keywords: Late hemolytic anemia, severe malaria, artesunate injection, Isangi

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