Pleural Effusion as Manifestation of IgG4 Related Disease
Published: 2021-06-11
Page: 89-95
Issue: 2021 - Volume 4 [Issue 1]
N. Kallel
*
Department of Pneumology, Hedi Chaker University Hospital, Sfax, Tunisia.
N. Mahmoud
Department of Pneumology, Hedi Chaker University Hospital, Sfax, Tunisia.
S. Charfi
Department of Anatomic Pathology, Habib Bourguiba Hospital, Sfax, Tunisia.
N. Moussa
Department of Pneumology, Hedi Chaker University Hospital, Sfax, Tunisia.
R. Gargouri
Department of Pneumology, Hedi Chaker University Hospital, Sfax, Tunisia.
N. Bahloul
Department of Pneumology, Hedi Chaker University Hospital, Sfax, Tunisia.
I. Yangui
Department of Pneumology, Hedi Chaker University Hospital, Sfax, Tunisia.
*Author to whom correspondence should be addressed.
Abstract
Immunoglobulin G4-related disease is a very rare and little known sclerosing inflammatory disease. This pathology has been reported in various organs. Of these, there are only 9 reports describing pleuritis as IgG4-related disease with no other organ involevement. We report the original observation of an isolated pleural effusion as manifestation of IgG4 related disease in a 60-year-old woman. We suggest the possibility to includ IgG4 related disease in the differential diagnosis of unexplained pleuritis. Our observation is distinguished by the isolated nature of pleural involvement and the spontaneous regression of pleural effusion.
Keywords: IgG4, inflammatory disease, plasma cells, pancreatitis, lung