The Adrenal Gland as a Rare Metastatic Site of Oesophageal Carcinoma: A Case Report
Ashish Wadekar
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Sunil Kumar Mallick
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Rimlee Dutta
*
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Naveen Gupta
Department of Surgical Oncology, National Cancer Institute, All India Institute of Medical Sciences, New Delhi, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Oesophageal squamous cell carcinoma (OSCC) frequently metastasizes to lymph nodes, liver, lung, bone and brain; adrenal involvement is rare and is detected incidentally or during autopsy.
Case Summary: Herein, we report a case of a 42-year-old male diagnosed with moderately differentiated OSCC. On imaging, distal oesophageal lesion with a left adrenal nodule was seen. Following neoadjuvant chemoradiotherapy, the patient underwent Ivor Lewis esophagectomy with left adrenalectomy. Histopathology confirmed adrenal metastasis from OSCC. The final stage was ypT3 ypN0 ypM1 (Stage IVB).
Conclusion: The present case highlights the importance of thorough metastatic workup in oesophageal cancer, as adrenal lesions may be the first or only sign of distant spread. Histopathological confirmation is crucial for guiding appropriate surgical and therapeutic decisions.
Keywords: Oesophageal carcinoma, Adrenal gland, metastasis, carcinoma, squamous cell carcinoma