Adult Granulosa Cell Tumour Presenting as a Huge Ovarian Mass in a Postmenopausal Woman: A Case Report and Review of Management
Oluwaseye F. Oyeniran *
Department of Obstetrics and Gynaecology, Carespring Specialist Hospital, Mowe, Ogun State, Nigeria.
Olubunmi O. Ogein
Department of Obstetrics and Gynaecology, Carespring Specialist Hospital, Mowe, Ogun State, Nigeria.
Joshua O. Awofeso
Department of Radiology, Redeemers Health Village (RHV), Ogun State, Nigeria.
Temitope E. Ogunsanya
Department of Histopathology, Redeemers Health Village (RHV), Ogun State, Nigeria.
Olatunbosun O. Olawanle
Department of Anaesthesiology and Intensive care, Carespring Specialist Hospital, Mowe, Ogun State, Nigeria.
Sampson C. Aliozor
Department of Paediatric Surgery, Carespring Specialist Hospital, Mowe, Ogun State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Background: Granulosa cell tumours (GCTs) are rare sex cord-stromal tumours of the ovary, accounting for less than 5% of all ovarian malignancies. Adult-type GCTs typically present in perimenopausal or postmenopausal women and can manifest with non-specific symptoms or hormonal effects such as postmenopausal bleeding.
Case Presentation: We report the case of a 65-year-old postmenopausal woman who presented with abdominal swelling and pain. Magnetic Resonance Imaging (MRI) and ultrasonography revealed a large abdomino-pelvic mass. Surgical exploration confirmed a huge ovarian tumour and she underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for an early-stage disease [FIGO stage IA]. Histopathological examination diagnosed an adult granulosa cell tumour. Her postoperative recovery was uneventful, and she is currently on surveillance with serum Inhibin B and Anti-Mullerian Hormone (AMH) levels for early detection of recurrence.
Conclusion: This case highlights the importance of considering granulosa cell tumour in the differential diagnosis of adnexal masses in postmenopausal women. Early recognition, appropriate surgical management and prolonged follow-up are essential due to the tumour’s potential for late recurrence as seen in the management of this patient who presented with FIGO stage IA disease.
Keywords: Adult granulosa cell tumour, huge, ovarian mass, postmenopausal