Mucinous Tubular and Spindle Cell Carcinoma: A Case Report and Review of the Literature
Ayoub Khaled
*
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Ismail Chaouche
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Moncef Oussafi
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Hajar Ouazzani Chahdi
Department of Mother and Child Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Amal Akammar
Department of Mother and Child Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Nizar El Bouardi
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Meriem Haloua
Department of Mother and Child Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Badreddine Alami
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Moulay Youssef Alaoui Lamrani
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Meryem Boubbou
Department of Mother and Child Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Mustapha Maaroufi
Department of Adult Radiology, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare epithelial renal tumor, first recognized as a distinct subtype of renal cell carcinoma (RCC) in the 2004 WHO classification. It is characterized by low malignant potential and typically indolent clinical behavior. Due to its rarity and overlapping imaging features with other renal tumors, accurate preoperative diagnosis remains challenging.
We report the case of a 42-year-old woman presenting with painless, non-clotting gross hematuria persisting for four months. Ultrasound revealed a suspicious renal mass, which was further evaluated by contrast-enhanced CT, showing a 12 cm heterogeneous lesion in the lower pole of the right kidney. The mass demonstrated areas of hemorrhage and punctate calcifications, along with delayed, progressive enhancement. There was no evidence of adjacent organ invasion. Histopathological examination following right radical nephrectomy confirmed the diagnosis of MTSCC.
Although the definitive diagnosis relies on histological examination, imaging plays a key role in detecting the tumor, assessing its contrast enhancement pattern, evaluating its morphological characteristics, and determining the extent of the lesion. These elements help guide the preoperative diagnosis, suggest potential histological subtypes, and support appropriate management planning, particularly in terms of surgical approach.
Keywords: Mucinous tubular and spindle cell carcinoma, computed tomography, renal mass, low-grade tumor