A Case Report on a Rare Diagnosis: Kikuchi’s Disease (Kikuchi-Fujimoto Disease)

Aditi Bhatnagar *

Department of Critical Care Medicine, Ramkrishna Care Hospital, Raipur (CG), India.

Vishal Kumar

Department of Critical Care Medicine, Ramkrishna Care Hospital, Raipur (CG), India.

Monika Singh

Department of Critical Care Medicine, Ramkrishna Care Hospital, Raipur (CG), India.

*Author to whom correspondence should be addressed.


Abstract

Kikuchi’s disease (Kikuchi-Fujimoto disease) is a rare, self-limiting condition characterized by necrotizing lymphadenitis, typically affecting young women, although it can also present in men.

All basic investigations were initially inconclusive. On further workup, CT scan showed enlarged lymph nodes raising our suspicion. Biopsy was performed, and histopathology showed necrotizing lymphadenitis. Immunohistochemistry confirmed the diagnosis of Kikuchi’s disease. The patient was treated and eventually discharged in stable condition. This case highlights the importance of considering Kikuchi’s disease in the differential diagnosis of young adults with fever, lymphadenopathy, and weight loss. Timely diagnosis through histopathological and immunohistochemical examination is crucial to avoid unnecessary interventions and ensure appropriate management.

Keywords: Kikuchi Fujimoto, necrotizing lymphadenitis, cervical lymphadenopathy, lymphatic disorder


How to Cite

Bhatnagar, Aditi, Vishal Kumar, and Monika Singh. 2025. “A Case Report on a Rare Diagnosis: Kikuchi’s Disease (Kikuchi-Fujimoto Disease)”. Asian Journal of Case Reports in Medicine and Health 8 (1):98-104. https://doi.org/10.9734/ajcrmh/2025/v8i1227.

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