Late-Onset Fibrodysplasia Ossificans Progressiva (FOP) or Munchmeyer’s Disease: A Case Report and Review of Clinical and Radiological Features
Israa Lassouli *
Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.
Dounia Younes
Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.
Khadija Echchilali
Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.
Mina Moudatir
Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.
Hassan EL Kabli
Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Fibrodysplasia ossificans progressive (FOP) is a rare variety of myositis ossificans characterized by congenital malformations of the great toes and progressive heterotopic ossification that can induce a disabling second skeleton. We report a case of a 37-year-old female patient with late-onset Fibrodysplasia Ossificans Progressiva (FOP), presenting with disabling ankylosis and progressive heterotopic ossification since adolescence following trauma. The report outlines the clinical, radiological, and evolutionary aspects of FOP, with a focus on the diagnosis through classic congenital malformations of the toes and progressive ossification patterns. The paper underscores the challenges of managing such a rare disease, where early diagnosis and genetic confirmation are crucial for prognosis.
Keywords: Munchmeyer’s disease, myositis ossificans, heterotopic ossification, hallux valgus