Generalized Bullous Pemphigoid and Glycaemic Control in the Geriatric age Group: A Case Report
Published: 2024-04-06
Page: 45-50
Issue: 2024 - Volume 7 [Issue 1]
Amadi, Ekechi Stella *
Department of Internal Medicine, Dermatology Unit, Rivers State University, Nkpolu-Oroworokwu, Rivers State University Teaching Hospital, Harley Street, Port Harcourt, Nigeria and Dermatology in Clinical Practice, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, United Kingdom.
Obioha, Solomon Uchenna
Anatomical Pathology, Faculty of Basic Clinical Sciences, Rivers State University, Rivers State University Teaching Hospital, Harley Street, Port Harcourt, Nigeria.
Gomba, Victoria Eno
Department of Internal Medicine, Endocrinology, Diabetes and Metabolism Unit, Rivers State University, Nkpolu-Oroworokwu, Rivers State University Teaching Hospital, Harley Street, Port Harcourt, Nigeria.
Amaewhule, Mary Nnenda
Department of Internal Medicine, Dermatology Unit, Rivers State University, Nkpolu-Oroworokwu, Rivers State University Teaching Hospital, Harley Street, Port Harcourt, Nigeria.
Figilo, Ibeinmo Moses
Department of Internal Medicine, Dermatology Unit, Rivers State University Teaching Hospital, Harley Street, Port Harcourt, Nigeria, Federal Medical Centre, Yenagoa, Nigeria.
Altraide, Dasetima Dandeson
Department of Internal Medicine, University of Port Harcourt, Dermatology Unit, Rivers State University Teaching Hospital, Harley Street, Port Harcourt, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Bullous pemphigoid (BP) is a rare autoimmunobullous disease which is seen more in the elderly. There are many factors that have been associated with BP including medications, vaccines, and different diseases including diabetes mellitus. Diabetes mellitus is known to enhance the production of autoantibodies by glycosylation of dermal proteins and increase skin fragility. This case report looks at the management of BP with consideration for glycaemic control; the accurate interpretation of the values in the older adult and emphasis on the need for multidisciplinary approach while also taking note of medication side effects.
Keywords: Corticosteroids, diabetes mellitus, generalized bullous pemphigoid, geriatric age, glycaemic control, rivaroxaban