Asian Journal of Case Reports in Medicine and Health

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) CIDP is a rare and heterogenous autoimmune disorder of the peripheral nervous system that attacks myelin sheath around the peripheral nerves. It is characterized by muscle weakness and sensory deficits, numbness that can lead to significant neurological disability evolving over more than 8 weeks. Raised protein concentrations in CSF and heterogeneous slowing of nerve conduction are typical of the condition. Understanding of its pathophysiology has recently improved, although its causes remain unclear. Diagnosis is sometimes challenging and can require use of neuro imaging and nerve biopsy. The diagnosis is also  based on a combination of clinical examination findings, electrodiagnostic studies, and other supportive evidence. Recognizing CIDP and distinguishing it from other chronic polyneuropathies is important because many patients with CIDP are highly responsive to treatment with corticosteriods, immunosuppressive or immunomodulatory therapies. This case report summarizes the variants of CIDP, diagnosis and current treatment strategies.