Metastatic Adenocarcinoma of the Rectum Revealed by Bilateral Occlusion of the Central Retinal Vein: A Case Report

A. Jahouh *

Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.

L. Barakat

Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.

K. Echchilali

Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.

M. Moudatir

Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.

H. El kabli

Department of Internal Medicine, Ibno Rochd University Hospital, Casablanca, Morocco.

*Author to whom correspondence should be addressed.


Abstract

Central retinal vein occlusion (CRVO) is caused by the formation of a thrombus in the central retinal vein, and constitutes an extreme diagnostic and therapeutic emergency due to its visual prognosis. The most frequent cause of CRVO is related to cardiovascular risk factors, although neoplasia is a very rare cause of CRVO. A few cases of CRVO secondary to cancer have been reported in the literature, the imputability of malignant pathology may be explained by the systemic procoagulant state observed during the latter.

We report the case of a patient who suddenly presented with CRVO and whose etiological work-up was in favor of metastatic rectal adenocarcinoma. This observation demonstrates the importance of systematically searching for a neoplastic source in any thrombosis that is atypical, even if it is distant from the thrombus.

Keywords: Central retinal vein occlusion, thromboembolic disease, rectal cancer, ocular vascular disease


How to Cite

Jahouh, A., Barakat , L., Echchilali , K., Moudatir , M., & H. El kabli. (2024). Metastatic Adenocarcinoma of the Rectum Revealed by Bilateral Occlusion of the Central Retinal Vein: A Case Report. Asian Journal of Case Reports in Medicine and Health, 7(1), 1–4. Retrieved from https://journalajcrmh.com/index.php/AJCRMH/article/view/178

Downloads

Download data is not yet available.

References

Wong TY, Larsen EKM, Klein R, et al. Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli : The Atherosclerosis Risk in Communities & Cardiovascular Health studies. Ophthalmology. 2005;112:540-7.

Rhizlane A. Occlusion bilatérale de la veine centrale de la rétine comme première manifestation d’un cancer de poumon, Journal français d’ophtalmologie. 2020;43:805—808.

Catherine creuzot-Garcher, Pascale Massin. Rapport SFO ; œdème maculaire des occlusions veineuses; 2016.

Klein R, Moss SE, Meuer SM et al. L'incidence cumulée sur 15 ans de l'occlusion de la veine rétinienne : l'étude sur les yeux de Beaver Dam. Arch Ophthalmo. 2008;126:51318. DOI: 10.1001/archopht.126.4.513

Ozkaya A, Ozkaya HM, Alkın Z et al. Incidental ‘early’ diagnosis of colorectal carcinoma by way of central retinal vein occlusion. J Fr Ophtalmol. 2014;37:73–4. DOI: 10.1016/j.jfo.2013.06.010

Szczepanik S, Kęcik D. Bilateral central retinal vein occlusion in a patient with disseminated metastatic renal cell carcinoma treated with sorafenib. Retin Cases Brief Rep. 2012; 6:148–50. DOI: 10.1097/ICB.0b013e3182160965

Veronica Castro-Navarro. Bilateral BRVO in a patient with recurrent prostate cancer. BMJ Case Reports. 2015;bcr2015212463.

Jaulim A, Ahmed B, Khanam T, Chatziralli IP. Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complicatations.

Oisseiev E, Ling J, Morse LS. Leukemic optic nerve infiltration complicated by retinal artery and vein occlusions. Retina. 2017;37(2):10.

Lip GY, Chin BS, Blann AD. Cancer and the prothrombotic state. Lancet Oncol. 2002;3(1):27‐34.

Caine GJ, Stonelake PS, Lip GY, Kehoe ST. The hypercoagulable state of malignancy: Pathogenesis and current debate. Neoplasia. 2002;4(6):465‐473.