Pancreatic Pseudocyst Masquerading as a Serous Cyst Adenoma: A Case Report

Faisal Ali *

Shifa International Hospital Islamabad, Pakistan.

*Author to whom correspondence should be addressed.


A pancreatic pseudocyst (PP) is a post-inflammatory collection of pancreatic enzymes and inflammatory exudates surrounded by a fibrous tissue wall. PPs are mainly formed in the pancreatic bed. It is seen more commonly after an episode of chronic pancreatitis and less commonly after acute pancreatitis. The main differential diagnoses in such cases include pancreatic cystic neoplasms such as mucinous cyst adenoma of the pancreas, serous cyst adenoma of the pancreas, pancreatic retention cyst, and other benign congenital lesions such as gastric duplication cysts. The incidence PPs is 0.5 to 1 in 100,000 hospital admission due to pancreatitis. Complications may include bleeding, rupture, infection, gastric outlet or biliary obstruction, and thrombus formation. These lesions are typically unilocular but can be thinly septated. 

Here we report a case of PP mimicking a benign cystic neoplasm, which is not typically confused with a PP. PP’s can be misdiagnosed on radiological imaging but correct diagnosis can be made through aspiration and microscopic examination of the fluid via EUS.

Keywords: Endoscopic Ultrasound (EUS), pancreatic pseudo cyst, cystic neoplasm

How to Cite

Ali , Faisal. 2023. “Pancreatic Pseudocyst Masquerading As a Serous Cyst Adenoma: A Case Report”. Asian Journal of Case Reports in Medicine and Health 6 (1):143-48.


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Dababneh Y, Mousa OY. Pancreatic Serous Cystadenoma. [Updated 2022 Oct 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.

Dietrich CF, Dong Y, Jenssen C, Ciaravino V, Hocke M, Wang WP, Burmester E, Moeller K, Atkinson NS, Capelli P, D’Onofrio M. Serous pancreatic neoplasia, data and review. World journal of gastroenterology. 2017;23(30):5567.

Bollen TL, Wessels FJ. Radiological workup of cystic neoplasms of the pancreas. Visceral Medicine. 2018; 34(3):182-90.

Choudhury SR, Mohanty S, Mohapatra D, Sahoo N, Panda A. An atypical presentation of pancreatic pseudocyst masquerading as solid pseudopapillary neoplasm of pancreas. Cureus. 2020;12(8).

Javadi S, Menias CO, Korivi BR, Shaaban AM, Patnana M, Alhalabi K, Elsayes KM. Pancreatic calcifications and calcified pancreatic masses: pattern recognition approach on CT. American Journal of Roentgenology. 2017;209(1): 77-87.

Yadav RK, Jiang X, Chen J. Differentiating benign from malignant pancreatic cysts on computed tomography. European Journal of Radiology Open. 2020;7: 100278.

Singh RR, Gopakumar H, Sharma NR. Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature. Diagnostics. 2023;13(3):550.

Nalwa HS, Lanka SP, Mederos R, Mederos Jr R. Giant Pseudocyst of the Pancreas: A Case Report. Cureus. 2022;14(9).

Agalianos C, Passas I, Sideris I, Davides D, Dervenis C. Review of management options for pancreatic pseudocysts. Translational Gastroenterology and Hepatology. 2018;3.

Nishi M, Akamatsu N, Sekiba K. Magnetic resonance imaging of the ovarian cyst: its diagnostic value of endometrial cyst. Medical progress through technology. 1990 Jan 1;16(4):201-12.

Pitchumoni CS, Agarwal N. Pancreatic pseudocysts: when and how should drainage be performed?. Gastroenterology Clinics of North America. 1999;28(3): 615-39.