Interstitial Nephritis as the Initial Presentation of Sjogren’s Syndrome: A Case Report with Review of Literature
Published: 2021-09-25
Page: 143-149
Issue: 2021 - Volume 4 [Issue 1]
Anirban Sen
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
Atanu Pal *
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
Ankit Ray
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
Koushik Bhattacharjee
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
Dipankar Sircar
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
Arpita Ray Chaudhury
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
Debabrata Sen
Department of Nephrology, IPGMER & SSKM Hospital, Kolkata, India.
*Author to whom correspondence should be addressed.
Abstract
Primary Sjögren’s syndrome is a rare autoimmune condition affecting the exocrine glands. However, extra-glandular manifestations are not uncommon and may present as the initial symptoms of this disorder. Such cases offer a great challenge to clinicians. Here we present a case of primary Sjögren’s syndrome, which presented with incidentally detected renal dysfunction which on investigation revealed distal renal tubular acidosis and tubulointerstitial nephritis. The patient responded to combined therapy of steroid and rituximab and is currently having a stable renal function.
Keywords: Interstitial nephritis, Sjögren Syndrome, extra-glandular features, distal renal tubular acidosis